BDBM430909 US10550102, Example (-)-20-3

SMILES CCc1cc(CN2CC(C)c3cccc(c23)-c2cccc(n2)-n2ncc(C(O)=O)c2C)ccc1C1CCN(CC1)C(=O)C1CC1

InChI Key InChIKey=NWALFBTUCMMLOY-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 430909   

TargetGuanylate cyclase soluble subunit alpha-1/beta-1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM430909(US10550102, Example (-)-20-3)
Affinity DataEC50:  0.5nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent