BDBM430933 Example 30-A. Ethyl 5-ethyl-6-((S)-3-(3-ethyl-4-(1-((S)-2-hydroxypropanoyl)piperidin-4-yl)phenoxy)-2,3-dihydro-1H-inden-4-yl)pyridin-2-yl)-1H-pyrazole-4-carboxylate::US10550102, Example 30

SMILES CCc1c(cnn1-c1cccc(n1)-c1cccc2CC[C@H](Oc3ccc(C4CCN(CC4)C(=O)[C@H](C)O)c(CC)c3)c12)C(O)=O

InChI Key InChIKey=CALSAVUQRHARLQ-ICACTRECSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 430933   

TargetGuanylate cyclase soluble subunit alpha-1/beta-1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM430933(Example 30-A. Ethyl 5-ethyl-6-((S)-3-(3-ethyl-4-(1...)
Affinity DataEC50:  0.5nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent