BDBM430947 Example 33-A. (S)-1-(6-(3-(4-(1-(tert-Butoxycarbonyl)piperidin-4-yl)-3-ethylphenoxy)-2,3-dihydro-1H-inden-4-yl)pyridin-2-yl)-5-ethyl-1H-pyrazole-4-carboxylic Acid::US10550102, Example 33

SMILES CCc1c(cnn1-c1cccc(n1)-c1cccc2CC[C@H](Oc3ccc(C4CCN(CC4)C(=O)C4(O)CC4)c(CC)c3)c12)C(O)=O

InChI Key InChIKey=XQSFRGIOOYAORA-YTTGMZPUSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 430947   

TargetGuanylate cyclase soluble subunit alpha-1/beta-1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM430947(Example 33-A. (S)-1-(6-(3-(4-(1-(tert-Butoxycarbon...)
Affinity DataEC50:  0.5nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent