BDBM43386 (E)-1-(2-prop-2-enylsulfanylbenzimidazol-1-yl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one::(E)-1-[2-(allylthio)benzimidazol-1-yl]-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one::(E)-1-[2-(prop-2-enylthio)-1-benzimidazolyl]-3-(3,4,5-trimethoxyphenyl)-2-propen-1-one::2-(allylthio)-1-[3-(3,4,5-trimethoxyphenyl)acryloyl]-1H-benzimidazole::MLS000577033::SMR000198113::cid_5737516

SMILES COc1cc(\C=C\C(=O)n2c(SCC=C)nc3ccccc23)cc(OC)c1OC

InChI Key InChIKey=JMBYFKBGOMJGFM-ZHACJKMWSA-N

Data  3 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 43386   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM43386((E)-1-(2-prop-2-enylsulfanylbenzimidazol-1-yl)-3-(...)
Affinity DataEC50:  270nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Brent Stockwell, Columbia University ML...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM43386((E)-1-(2-prop-2-enylsulfanylbenzimidazol-1-yl)-3-(...)
Affinity DataEC50:  1.16E+3nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Brent Stockwell, Columbia University ML...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM43386((E)-1-(2-prop-2-enylsulfanylbenzimidazol-1-yl)-3-(...)
Affinity DataEC50:  1.50E+6nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Brent Stockwell, Columbia University ML...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDNA damage-inducible transcript 3 protein(Mus musculus)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM43386((E)-1-(2-prop-2-enylsulfanylbenzimidazol-1-yl)-3-(...)
Affinity DataIC50:  4.56E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDNA damage-inducible transcript 3 protein(Mus musculus)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM43386((E)-1-(2-prop-2-enylsulfanylbenzimidazol-1-yl)-3-(...)
Affinity DataIC50:  4.56E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetX-box-binding protein 1(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM43386((E)-1-(2-prop-2-enylsulfanylbenzimidazol-1-yl)-3-(...)
Affinity DataIC50:  1.65E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM43386((E)-1-(2-prop-2-enylsulfanylbenzimidazol-1-yl)-3-(...)
Affinity DataEC50:  1.03E+4nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay