BDBM434517 US10562893, Compound 9

SMILES C[C@H](NCc1ccc2n(c(NC(=O)c3cccc(c3)C#N)nc2c1)-c1cccc(NC(=O)C=C)c1)C(C)(C)C

InChI Key InChIKey=JNXRDFRLWNVVMK-FQEVSTJZSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 434517   

TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Gb005

US Patent
LigandPNGBDBM434517(US10562893, Compound 9)
Affinity DataEC50: <10nMAssay Description:ITK: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-diluted ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Tec(Homo sapiens (Human))
Gb005

US Patent
LigandPNGBDBM434517(US10562893, Compound 9)
Affinity DataEC50:  55nMAssay Description:Tec: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-diluted ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Gb005

US Patent
LigandPNGBDBM434517(US10562893, Compound 9)
Affinity DataEC50: <10nMAssay Description:RLK/TXK: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent