BDBM434573 US10562900, Example 70
SMILES COc1cc(OC)c(Cl)c(c1Cl)-c1ccc2c(NC(=O)c3ccc(cc3)N3CCOCC3)n[nH]c2n1
InChI Key InChIKey=WLVKMBHRLFROHY-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 434573
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Shanghai Haihe Pharmaceutical
US Patent
Shanghai Haihe Pharmaceutical
US Patent
Affinity DataIC50: <100nMAssay Description:The enzyme reaction substrate Poly(Glu,Tyr) 4:1 was diluted with PBS without potassium ion (10 mM sodium phosphate buffer, 150 mM NaCl, pH7.2-7.4) to...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Shanghai Haihe Pharmaceutical
US Patent
Shanghai Haihe Pharmaceutical
US Patent
Affinity DataIC50: 7.70nMAssay Description:Inhibition of recombinant human FGFR1 using poly (Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Shanghai Haihe Pharmaceutical
US Patent
Shanghai Haihe Pharmaceutical
US Patent
Affinity DataIC50: 7.70nMAssay Description:Inhibition of recombinant human FGFR1 using poly (Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Shanghai Haihe Pharmaceutical
US Patent
Shanghai Haihe Pharmaceutical
US Patent
Affinity DataIC50: <100nMAssay Description:The enzyme reaction substrate Poly(Glu,Tyr) 4:1 was diluted with PBS without potassium ion (10 mM sodium phosphate buffer, 150 mM NaCl, pH7.2-7.4) to...More data for this Ligand-Target Pair