BDBM435897 2-(2-chlorophenyl)-1-((1S,3R)- 3-(hydroxymethyl)-1-methyl- 5-(1-methyl-1H-pyrazol-4-yl)- 3,4-dihydroisoquinolin-2(1H)- yl)ethan-1-one::US10611751, Example 7
SMILES C[C@@H]1N([C@@H](CO)Cc2c1cccc2-c1cnn(C)c1)C(=O)Cc1ccccc1Cl
InChI Key InChIKey=NUZBWQNSAWYYEI-MAUKXSAKSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 435897
Affinity DataEC50: 81nMAssay Description:Positive allosteric modulation of human D1 receptor expressed in HEK293 assessed as cAMP production incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 81.2nMAssay Description:The PAM activity of the compounds of the present invention may be measured essentially as described in Svensson et al., An Allosteric Potentiator of ...More data for this Ligand-Target Pair