BDBM436044 2-(2-chloro-4-fluorophenyl)-1- ((1S,3R)-3-(hydroxymethyl)-1- methyl-5-(1H-pyrazol-4-yl)- 3,4-dihydroisoquinolin-2(1H)- yl)ethan-1-one::US10611751, Example 12
SMILES C[C@@H]1N([C@@H](CO)Cc2c1cccc2-c1cn[nH]c1)C(=O)Cc1ccc(F)cc1Cl
InChI Key
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 436044
Affinity DataEC50: 540nMAssay Description:Positive allosteric modulation of human D1 receptor expressed in HEK293 assessed as cAMP production incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 540nMAssay Description:The PAM activity of the compounds of the present invention may be measured essentially as described in Svensson et al., An Allosteric Potentiator of ...More data for this Ligand-Target Pair