BDBM436176 US10590106, Compound C001

SMILES FC(F)(F)c1cc(NC(=O)Nc2cccc(Oc3ccc4nccnc4c3)c2)ccc1Cl

InChI Key InChIKey=GOBIAUMHSSKXFE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 436176   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Neupharma

US Patent
LigandPNGBDBM436176(US10590106, Compound C001)
Affinity DataIC50: <100nMAssay Description:Inhibitory activities of compounds against KDR (VEGFR2) were also measured by Invitrogen using Z'-LYTE Method as described above with the following m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Neupharma

US Patent
LigandPNGBDBM436176(US10590106, Compound C001)
Affinity DataIC50: >100nMAssay Description:Inhibitory activities Inhibitory activities of compounds against BRAF, and BRAF V600E were measured by Invitrogen using Z′-LYTEŽ Method as brie...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent