BDBM437288 1-methyl-5-(1-(1-(o-tolyl)ethyl)-1H-pyrazol-4-yl) pyridin-2(1H)-one::US10617680, Example 22::US11020380, Example 22

SMILES CC(c1ccccc1C)n1cc(cn1)-c1ccc(=O)n(C)c1

InChI Key InChIKey=QYLUEABEKSHVNT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437288   

TargetCREB-binding protein(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM437288(1-methyl-5-(1-(1-(o-tolyl)ethyl)-1H-pyrazol-4-yl) ...)
Affinity DataIC50: <500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM437288(1-methyl-5-(1-(1-(o-tolyl)ethyl)-1H-pyrazol-4-yl) ...)
Affinity DataIC50: <500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent