BDBM437653 2-cyclopropyl-6-[4-[4-[6-(2-fluoroethoxy)-3-pyridyl]-1- methyl-6-oxo-3-pyridyl]pyrazol-1-yl]benzonitrile::US10617680, Example 387::US11020380, Example 387

SMILES Cn1cc(-c2cnn(c2)-c2cccc(C3CC3)c2C#N)c(cc1=O)-c1ccc(OCCF)nc1

InChI Key InChIKey=ZSGRMMGFRQFHOX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437653   

TargetCREB-binding protein(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM437653(2-cyclopropyl-6-[4-[4-[6-(2-fluoroethoxy)-3-pyridy...)
Affinity DataIC50: <500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM437653(2-cyclopropyl-6-[4-[4-[6-(2-fluoroethoxy)-3-pyridy...)
Affinity DataIC50: <500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent