BDBM437654 2-cyclopropyl-6-(4-(1'-cyclopropyl-1-methyl-2',6-dioxo- 1,1',2',6-tetrahydro-[4,4'-bipyridin]-3-yl)-1H-pyrazol-1- yl)benzonitrile::US10617680, Example 388::US11020380, Example 388

SMILES Cn1cc(-c2cnn(c2)-c2cccc(C3CC3)c2C#N)c(cc1=O)-c1ccn(C2CC2)c(=O)c1

InChI Key InChIKey=RVBGJTMWJQYFIB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437654   

TargetCREB-binding protein(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM437654(2-cyclopropyl-6-(4-(1'-cyclopropyl-1-methyl-2',6-d...)
Affinity DataIC50: <500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM437654(2-cyclopropyl-6-(4-(1'-cyclopropyl-1-methyl-2',6-d...)
Affinity DataIC50: <500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent