BDBM437656 2-cyclopropyl-6-[4-[4-[1-(2-hydroxyethyl)-2-oxo-4- pyridyl]-1-methyl-6-oxo-3-pyridyl]pyrazol-1- yl]benzonitrile::US10617680, Example 390::US11020380, Example 390

SMILES Cn1cc(-c2cnn(c2)-c2cccc(C3CC3)c2C#N)c(cc1=O)-c1ccn(CCO)c(=O)c1

InChI Key InChIKey=ZVYDKFWBSOEWTD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437656   

TargetCREB-binding protein(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM437656(2-cyclopropyl-6-[4-[4-[1-(2-hydroxyethyl)-2-oxo-4-...)
Affinity DataIC50: <500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM437656(2-cyclopropyl-6-[4-[4-[1-(2-hydroxyethyl)-2-oxo-4-...)
Affinity DataIC50: <500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent