BDBM444467 US10662159, Example 56

SMILES FC(F)(F)Oc1cccc(OC2CC3(C2)CN(C3)C(=O)OC(C(F)(F)F)C(F)(F)F)c1

InChI Key InChIKey=HQYWEWCBSUGRQV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 444467   

TargetMonoglyceride lipase(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444467(US10662159, Example 56)
Affinity DataIC50:  550nMAssay Description:MGL: Compound inhibition of hMGL activity was assessed by a fluorometric assay recently developed in our laboratory (Makriyannis et al WO Patent Appl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444467(US10662159, Example 56)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent