BDBM444508 (R)-4-(1-benzylpyrrolidin-3-ylamino)-3-chloro- N-(thiazol-2-yl)benzenesulfonamide::US10662184, Example 79
SMILES Clc1cc(ccc1N[C@@H]1CCN(C1)c1ccccc1)S(=O)(=O)Nc1nccs1
InChI Key InChIKey=OKOHOURYIJIWAH-CQSZACIVSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 444508
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
US Patent
Xenon Pharmaceuticals
US Patent
Affinity DataIC50: >1.00E+4nMAssay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
US Patent
Xenon Pharmaceuticals
US Patent
Affinity DataIC50: 138nMAssay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair