BDBM444511 (S)-3-chloro-4-(methyl(1-(3- methylbenzyl)pyrrolidin-3-yl)amino)-N-(1,2,4- thiadiazol-5-yl)benzenesulfonamide::US10662184, Example 83
SMILES Cc1cccc(CN2CC[C@@H](C2)Nc2ccc(cc2Cl)S(=O)(=O)Nc2ncns2)c1
InChI Key InChIKey=MVUZMVLLJHYYJQ-INIZCTEOSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 444511
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
US Patent
Xenon Pharmaceuticals
US Patent
Affinity DataIC50: >1.00E+4nMAssay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
US Patent
Xenon Pharmaceuticals
US Patent
Affinity DataIC50: 36nMAssay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair