BDBM444513 (R)-5-chloro-2-fluoro-4-(1-(3- methylbenzyl)pyrrolidin-3-ylamino)-N-(thiazol- 2-yl)benzenesulfonamide::US10662184, Example 88

SMILES Cc1cccc(c1)N1CC[C@@H](C1)Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1nccs1

InChI Key InChIKey=LSKHZCVLYTUIQZ-AWEZNQCLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 444513   

TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM444513((R)-5-chloro-2-fluoro-4-(1-(3- methylbenzyl)pyrrol...)
Affinity DataIC50:  1.25E+3nMAssay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM444513((R)-5-chloro-2-fluoro-4-(1-(3- methylbenzyl)pyrrol...)
Affinity DataIC50:  39nMAssay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent