BDBM444514 (R)-4-(1-benzylpyrrolidin-3-ylamino)-5-chloro- 2-fluoro-N-(thiazol-2-yl)benzenesulfonamide::US10662184, Example 89
SMILES Fc1cc(N[C@@H]2CCN(C2)c2ccccc2)c(Cl)cc1S(=O)(=O)Nc1nccs1
InChI Key InChIKey=IXJXVJVVOXLEOM-CYBMUJFWSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 444514
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
US Patent
Xenon Pharmaceuticals
US Patent
Affinity DataIC50: 2.87E+3nMAssay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
US Patent
Xenon Pharmaceuticals
US Patent
Affinity DataIC50: 91nMAssay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair