BDBM445059 US10669227, Compound 5::US11608309, Compound 5
SMILES C[NH2+]Cc1ccc(\C=C\C(=O)CC(=O)\C=C\c2ccc(cc2)[NH+](C)C)cc1
InChI Key InChIKey=BGDSIMSIIUZPPX-WFYKWJGLSA-P
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 445059
TargetNeutrophil collagenase(Homo sapiens (Human))
The Research Foundation For The State University of New York
US Patent
The Research Foundation For The State University of New York
US Patent
Affinity DataIC50: 2.80E+4nMAssay Description:Table 1 shows the IC50 of curcumin, compound 1, and compound 2, compared to a standard Zn++ binding & MMPI (matrix metalloproteinase inhibitor), 1,10...More data for this Ligand-Target Pair
TargetNeutrophil collagenase(Homo sapiens (Human))
The Research Foundation For The State University of New York
US Patent
The Research Foundation For The State University of New York
US Patent
Affinity DataIC50: 2.80E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair