BDBM445524 2-{7-[4-(2H3)Methyl-1-methyl-1H-1,2,3-triazol-5-yl]-5-[(S)-oxan-4-yl(phenyl)methyl]-5H-pyrido[3,2-b]indol-3-yl}propan-2-ol::US10683290, Example 16
SMILES Cc1nnn(C)c1-c1ccc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc(cnc21)C(C)(C)O
InChI Key InChIKey=LHUPUFVIXSYKRE-GDLZYMKVSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 445524
Affinity DataIC50: <5nMAssay Description:All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development
Curated by ChEMBL
Bristol Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
TargetMyc proto-oncogene protein(Homo sapiens (Human))
Bristol Myers Squibb Research And Development
Curated by ChEMBL
Bristol Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of c-MYC (unknown origin)More data for this Ligand-Target Pair