BDBM445786 US10669240, Compound 82

SMILES CC1CCN(Cc2cncc(c2)-c2ccc3[nH]nc(C(=O)Nc4cccnc4)c3c2)CC1

InChI Key InChIKey=OLUJPDZZXTUOGS-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 445786   

TargetProto-oncogene Wnt-1(Homo sapiens (human))
Samumed

US Patent
LigandPNGBDBM445786(US10669240, Compound 82)
Affinity DataIC50:  7nMAssay Description:Reporter cell lines were generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a W...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPulmonary surfactant-associated protein A1(Human)
Samumed

US Patent
LigandPNGBDBM445786(US10669240, Compound 82)
Affinity DataIC50:  129nMAssay Description:Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 8-point dose-response curves f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM445786(US10669240, Compound 82)
Affinity DataEC50:  2nMAssay Description:SH-SY5Y cells are cultured in DMEM/F-12 medium supplemented with 15% FBS, Non-essential Amino Acid and Penicillin/Streptamycin. Two days before treat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent