BDBM445953 US10669246, Example 5::US10968188, Example 5
SMILES Cc1ccncc1-c1ccc2nc(NC(=O)C3CC3)sc2c1
InChI Key InChIKey=JHDSITICBSAFEJ-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 445953
Affinity DataIC50: 9nMAssay Description:c-abl kinase activity was measured by Promega's ADP-Glo™ Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/μl) is incubated w...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
1St Biotherapeutics
US Patent
1St Biotherapeutics
US Patent
Affinity DataIC50: 1.61E+3nMAssay Description:PDGFRα kinase activity was measured by Promega's ADP-Glo™ Assay. In this assay, Recombinant human PDGFRα (40 ng) is incubated with 5 ...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:c-abl kinase activity was measured by Promega's ADP-Glo™ Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/μl) is incubated w...More data for this Ligand-Target Pair