BDBM445953 US10669246, Example 5::US10968188, Example 5

SMILES Cc1ccncc1-c1ccc2nc(NC(=O)C3CC3)sc2c1

InChI Key InChIKey=JHDSITICBSAFEJ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 445953   

TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
1St Biotherapeutics

US Patent
LigandPNGBDBM445953(US10669246, Example 5 | US10968188, Example 5)
Affinity DataIC50:  9nMAssay Description:c-abl kinase activity was measured by Promega's ADP-Glo™ Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/μl) is incubated w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
1St Biotherapeutics

US Patent
LigandPNGBDBM445953(US10669246, Example 5 | US10968188, Example 5)
Affinity DataIC50:  1.61E+3nMAssay Description:PDGFRα kinase activity was measured by Promega's ADP-Glo™ Assay. In this assay, Recombinant human PDGFRα (40 ng) is incubated with 5 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
1St Biotherapeutics

US Patent
LigandPNGBDBM445953(US10669246, Example 5 | US10968188, Example 5)
Affinity DataIC50:  9nMAssay Description:c-abl kinase activity was measured by Promega's ADP-Glo™ Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/μl) is incubated w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent