BDBM446739 (1R,2R,3R,5R,6R)-2-amino-6-fluoro-3-[(3- fluorophenyl)methoxy]bicyclo[3.1.0]hexane-2.6- dicarboxylic acid::US10689327, Compound (II)-6

SMILES N[C@@]1([C@H]2[C@@H](C[C@H]1OCc1cccc(F)c1)[C@]2(F)C(O)=O)C(O)=O

InChI Key InChIKey=YKPDUULXXDPIGO-ZNLHFFCSSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 446739   

TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM446739((1R,2R,3R,5R,6R)-2-amino-6-fluoro-3-[(3- fluorophe...)
Affinity DataIC50:  75.5nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM446739((1R,2R,3R,5R,6R)-2-amino-6-fluoro-3-[(3- fluorophe...)
Affinity DataIC50:  27.8nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent