BDBM447719 3-([1,1'-biphenyl]-4-yl)-1-(1- cyanopyrrolidin-3-yl)-1-methylurea::US10689345, Example 259::US11066365, Example 259

SMILES CN(C1CCN(C1)C#N)C(=O)Nc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=GWDQHNQUCHQQRO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 447719   

TargetUbiquitin carboxyl-terminal hydrolase 30(Homo sapiens (Human))
Mission Therapeutics

US Patent
LigandPNGBDBM447719(3-([1,1'-biphenyl]-4-yl)-1-(1- cyanopyrrolidin-3-y...)
Affinity DataIC50: <100nMAssay Description:USP30 biochemical fluorescence intensity IC50 assay Dilution plates were prepared at 21 times the final concentration (2100 μM for a final conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30(Homo sapiens (Human))
Mission Therapeutics

US Patent
LigandPNGBDBM447719(3-([1,1'-biphenyl]-4-yl)-1-(1- cyanopyrrolidin-3-y...)
Affinity DataIC50: <100nMAssay Description:USP30 Biochemical Fluorescence Intensity Kinetic Assay.Reactions were performed in duplicate in black 384 well plates (small volume, Greiner 784076) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent