BDBM448641 5-(7-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)-N,1-dimethyl-7-(prop-1-en-2-yl)-1H-indole-3-carboxamide::US10696655, Example 107::US11168070, Example 107

SMILES CNC(=O)c1cn(C)c2c(cc(cc12)N1CCCc2cc(-c3cnn(C)c3)c(cc12)C(F)F)C(C)=C

InChI Key InChIKey=WQLKPEJEQYTNPB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 448641   

TargetCREB-binding protein(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM448641(5-(7-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)...)
Affinity DataIC50:  16nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM448641(5-(7-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)...)
Affinity DataIC50:  16nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent