BDBM448654 7-(difluoromethyl)-N-methyl-6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydro-2H-[1,8′-biquinoline]-2′-carboxamide::US10696655, Example 120::US11168070, Example 120

SMILES CNC(=O)c1ccc2cccc(N3CCCc4cc(-c5cnn(C)c5)c(cc34)C(F)F)c2n1

InChI Key InChIKey=LWAQJYLHDNSVQX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 448654   

TargetCREB-binding protein(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM448654(7-(difluoromethyl)-N-methyl-6-(1-methyl-1H-pyrazol...)
Affinity DataIC50:  6nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM448654(7-(difluoromethyl)-N-methyl-6-(1-methyl-1H-pyrazol...)
Affinity DataIC50:  6nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent