BDBM448908 US10696672, Compound 140::US10696672, Compound 141::US11634418, Compound 140

SMILES OC(=O)[C@H](CCN1C2CCC1C(CCc1ccc3CCCNc3n1)C2)NC(=O)c1cc(F)cc(c1)C(F)(F)F

InChI Key InChIKey=LSDXDHKWRNVRNF-GNVNLSDTSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 448908   

TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Pliant Therapeutics

US Patent
LigandPNGBDBM448908(US10696672, Compound 140 | US10696672, Compound 14...)
Affinity DataIC50: >1.00E+3nMAssay Description:Microplates were coated with recombinant human integrin αvβ6 (2 ug/ml) in PBS (100 ul/well 25° C., overnight). The coating solution was rem...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Pliant Therapeutics

US Patent
LigandPNGBDBM448908(US10696672, Compound 140 | US10696672, Compound 14...)
Affinity DataIC50: >1.00E+3nMAssay Description:Microplates were coated with recombinant human integrin αvβ6 (2 ug/ml) in PBS (100 ul/well 25° C. overnight). The coating solution was remo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Pliant Therapeutics

US Patent
LigandPNGBDBM448908(US10696672, Compound 140 | US10696672, Compound 14...)
Affinity DataIC50: <50nMAssay Description:Microplates were coated with recombinant human integrin αvβ6 (2 ug/ml) in PBS (100 ul/well 25° C., overnight). The coating solution was rem...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent