BDBM450350 US10676431, Example 113::US11117861, Example 113

SMILES CC1(C)CN(C(=O)[C@@H]1NC(=O)Nc1ccc(Cl)cc1F)c1ccc(c(F)c1F)-c1cccnc1P(C)(C)=O

InChI Key InChIKey=JOOVJTBMQARIMY-QFIPXVFZSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 450350   

TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM450350(US10676431, Example 113 | US11117861, Example 113)
Affinity DataEC50:  0.390nMAssay Description:A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (200 μM final) were added to 384-well Proxiplates (Perki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM450350(US10676431, Example 113 | US11117861, Example 113)
Affinity DataEC50:  590nMAssay Description:FPR2 and FPR1 Cyclic Adenosine Monophosphate (cAMP) Assays. A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM450350(US10676431, Example 113 | US11117861, Example 113)
Affinity DataEC50:  0.390nMAssay Description:FPR2 and FPR1 Cyclic Adenosine Monophosphate (cAMP) Assays. A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM450350(US10676431, Example 113 | US11117861, Example 113)
Affinity DataEC50:  590nMAssay Description:A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (200 μM final) were added to 384-well Proxiplates (Perki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent