BDBM450551 N-[(3-Chloro-4- cyanophenyl)methyl]-N- methyl-2-(4-oxo-6- piperidin-4-ylquinazolin- 3-yl)acetamide (intermediate A-9) and 2- isopropoxyacetic acid ([CAS RN 33445-07-7])::US10676446, Example 135

SMILES CC(C)OCC(=O)N1CCC(CC1)c1ccc2ncn(CC(=O)N(C)Cc3ccc(C#N)c(Cl)c3)c(=O)c2c1

InChI Key InChIKey=PJMCCJYXMLDXBR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 450551   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM450551(N-[(3-Chloro-4- cyanophenyl)methyl]-N- methyl-2-(4...)
Affinity DataIC50:  1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent