BDBM451731 4-(2-amino-5-(2-fluoro-5- nitrophenyl)pyridin-3-yl)-2- chlorobenzamide::US10710978, Compound I-30

SMILES NC(=O)c1ccc(cc1Cl)-c1cc(cnc1N)-c1cc(ccc1F)[N+]([O-])=O

InChI Key InChIKey=RVKRISLPYBUFST-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 451731   

TargetSerine/threonine-protein kinase 4(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM451731(4-(2-amino-5-(2-fluoro-5- nitrophenyl)pyridin-3-yl...)
Affinity DataIC50:  550nMAssay Description:Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase 26(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM451731(4-(2-amino-5-(2-fluoro-5- nitrophenyl)pyridin-3-yl...)
Affinity DataIC50: >1.00E+3nMAssay Description:Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase 24(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM451731(4-(2-amino-5-(2-fluoro-5- nitrophenyl)pyridin-3-yl...)
Affinity DataIC50: >1.00E+3nMAssay Description:Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM451731(4-(2-amino-5-(2-fluoro-5- nitrophenyl)pyridin-3-yl...)
Affinity DataIC50: >1.00E+3nMAssay Description:Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent