BDBM453277 US10729710, Compound (Ib)

SMILES CCCN1CCC[C@@H]2Cc3c4OCOc4ccc3C[C@@H]12

InChI Key InChIKey=DKFJCEPDDQVHLK-UKRRQHHQSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 453277   

TargetD(1A) dopamine receptor(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM453277(US10729710, Compound (Ib))
Affinity DataEC50: >1.00E+3nMAssay Description:Dopamine D1 receptor agonism was measured using a HTRF cAMP from CisBio using the protocol developed by HD Biosciences (China). Briefly, the assay is...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Mus musculus (Mouse))
H. Lundbeck

US Patent
LigandPNGBDBM453277(US10729710, Compound (Ib))
Affinity DataEC50:  3.80nMAssay Description:Evaluation of the agonist activity of compounds (I), (Ia) and (Ib) at the human 5-HT2B receptor was performed by Eurofins/Cerep (France) measuring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM453277(US10729710, Compound (Ib))
Affinity DataEC50:  46nMAssay Description:Dopamine D2 receptor agonism was measured using a calcium mobilization assay protocol developed by HD Biosciences (China). Briefly, HEK293/G15 cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent