BDBM454193 US10717708, Example 125::US11186544, Example 125::US11530183, Example 125

SMILES Fc1cccc(c1F)-c1ccc(cc1)N1CCC[C@@H](NC(=O)Nc2ccc(cc2)C(F)(F)F)C1=O

InChI Key InChIKey=KHDDMIHUEBVOEP-OAQYLSRUSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 454193   

TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM454193(US10717708, Example 125 | US11186544, Example 125 ...)
Affinity DataEC50:  9nMAssay Description:FPR2 and FPR1 Cyclic Adenosine Monophosphate (cAMP) Assays. A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM454193(US10717708, Example 125 | US11186544, Example 125 ...)
Affinity DataEC50:  330nMAssay Description:FPR2 and FPR1 Cyclic Adenosine Monophosphate (cAMP) Assays. A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM454193(US10717708, Example 125 | US11186544, Example 125 ...)
Affinity DataEC50:  330nMAssay Description:A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (200 μM final) were added to 384-well Proxiplates (Perki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM454193(US10717708, Example 125 | US11186544, Example 125 ...)
Affinity DataEC50:  330nMAssay Description:A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (200 μM final) were added to 384-well Proxiplates (Perki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM454193(US10717708, Example 125 | US11186544, Example 125 ...)
Affinity DataEC50:  9nMAssay Description:A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (200 μM final) were added to 384-well Proxiplates (Perki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM454193(US10717708, Example 125 | US11186544, Example 125 ...)
Affinity DataEC50:  9nMAssay Description:A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (200 μM final) were added to 384-well Proxiplates (Perki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent