BDBM454548 US10717746, Example 31

SMILES Clc1cnc(NC(=O)[C@H]2CCC[C@H](C2)NC(=O)CC#N)cc1-c1cnn2CCCCc12

InChI Key InChIKey=YAIMMOURHYBPBU-LSDHHAIUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 454548   

TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM454548(US10717746, Example 31)
Affinity DataIC50:  12nMAssay Description:Activity of CDK9 was determined in-vitro using a mobility shift assay on a Caliper LC3000 reader (Caliper/PerkinElmer), which measures fluorescence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM454548(US10717746, Example 31)
Affinity DataIC50: <3nMAssay Description:Activity of CDK9 was determined in-vitro using a mobility shift assay on a Caliper LC3000 reader (Caliper/PerkinElmer), which measures fluorescence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent