BDBM455049 US10730874, Compound I-73::US11352356, Compound I-73

SMILES OC(=O)CCc1nn(Cc2cn3cc(ccc3n2)C2CC2)cc1C(=O)NCc1ncn2ccc(Cl)cc12

InChI Key InChIKey=QXPVQRNZDQJGMB-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 455049   

TargetPlasma kallikrein(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM455049(US10730874, Compound I-73 | US11352356, Compound I...)
Affinity DataEC50: <1nMAssay Description:Example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing a fluorogenic peptide s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM455049(US10730874, Compound I-73 | US11352356, Compound I...)
Affinity DataEC50: <1nMAssay Description:Example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing a fluorogenic peptide s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent