BDBM455062 US10730874, Compound I-86

SMILES OC(=O)Cc1cc(cn2cc(Cn3cc(C(=O)NCc4ncn5ccc(Cl)cc45)c(n3)C3CC3)nc12)C1CC1

InChI Key InChIKey=KAOLMMGUXDLOJR-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 455062   

TargetPlasma kallikrein(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM455062(US10730874, Compound I-86)
Affinity DataEC50: <1nMAssay Description:Example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing a fluorogenic peptide s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM455062(US10730874, Compound I-86)
Affinity DataEC50: <1nMAssay Description:Example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing a fluorogenic peptide s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent