BDBM45592 1-(3,4-dimethoxyphenyl)-2-mesyl-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline::1-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-(methylsulfonyl)-1,2,3,4-tetrahydroisoquinoline::1-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-methylsulfonyl-3,4-dihydro-1H-isoquinoline::MLS000862297::SMR000300730::cid_2969665

SMILES COc1ccc(cc1OC)C1N(CCc2cc(OC)c(OC)cc12)S(C)(=O)=O

InChI Key InChIKey=RIIYMTKJORVDNL-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 45592   

TargetCoagulation factor XII(Human)
Pcmd

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 45592BDBM45592(1-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-methylsulf...)
Affinity DataIC50: 5.00E+4nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 45592BDBM45592(1-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-methylsulf...)
Affinity DataIC50: 5.00E+4nMAssay Description:Dose Response Confirmation for Small Molecule Inhibitors of Eukaryotic Translation Initiation NIH Molecular Libraries Screening Centers Network [MLSC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetPOsterior Segregation(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 45592BDBM45592(1-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-methylsulf...)
Affinity DataEC50:  3.00E+5nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2011
Entry Details
PCBioAssay
TargetZinc finger protein mex-5(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 45592BDBM45592(1-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-methylsulf...)
Affinity DataEC50:  3.00E+5nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2011
Entry Details
PCBioAssay