BDBM456008 2-(3-(cyclopropylethynyl)-7- (1-(2-methoxyethyl)-3- methyl-1H-pyrazol-4-yl)-2H- indazol-2-yl)-N-hydroxy-3- phenylpropanamide::US10723705, No. I-0165

SMILES COCCn1cc(c(C)n1)-c1cccc2c(C#CC3CC3)n(nc12)C(Cc1ccccc1)C(=O)NO

InChI Key InChIKey=CXCSVTQJYLKOGR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 456008   

TargetHistone deacetylase 8(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM456008(2-(3-(cyclopropylethynyl)-7- (1-(2-methoxyethyl)-3...)
Affinity DataIC50: <50nMAssay Description:HDAC-Glo I/II Assay Kit was purchased from Promega Corporation (Madison, Wis.), including the following components: HDAC-Glo I/II Buffer (25 mM Tris ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent