BDBM456050 2-(3- (cyclopropylethynyl)-7- (pyrimidin-5-yl)-2H- pyrazolo[3,4-c]pyridin-2- yl)-N-hydroxy-3- phenylpropanamide::US10723705, No. I-0207

SMILES ONC(=O)C(Cc1ccccc1)n1nc2c(nccc2c1C#CC1CC1)-c1cncnc1

InChI Key InChIKey=INQHJTRERUZSQW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 456050   

TargetHistone deacetylase 8(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM456050(2-(3- (cyclopropylethynyl)-7- (pyrimidin-5-yl)-2H-...)
Affinity DataIC50: <50nMAssay Description:HDAC-Glo I/II Assay Kit was purchased from Promega Corporation (Madison, Wis.), including the following components: HDAC-Glo I/II Buffer (25 mM Tris ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent