BDBM456088 US10723723, Example 45

SMILES Cc1c2COC(=O)c2ccc1[C@@H](O)CNCc1cnc(nc1)-n1cnc(c1)C#N

InChI Key InChIKey=NLQUBMHPJYPNII-SFHVURJKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 456088   

TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM456088(US10723723, Example 45)
Affinity DataIC50:  12nMAssay Description:Solutions and reagents: Thallium flux assay was performed using FluxOR kit (F10017, Life Technologies). Loading buffer, assay buffer and stimulus buf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent