BDBM456198 (R)-3-cyclopropyl-1-(5- (((2-hydroxy-2-(4-methyl- 1-oxo-1,3- dihydroisobenzofuran-5- yl)ethyl)amino)methyl) pyridin-2-yl)-1H-pyrazole-4- carbonitrile::US10723723, Example 116
SMILES Cc1c2COC(=O)c2ccc1[C@@H](O)CNCc1ccc(nc1)-n1cc(C#N)c(n1)C1CC1
InChI Key InChIKey=JYVHDLOOORQHHA-NRFANRHFSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 456198
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 20nMAssay Description:Solutions and reagents: Thallium flux assay was performed using FluxOR kit (F10017, Life Technologies). Loading buffer, assay buffer and stimulus buf...More data for this Ligand-Target Pair