BDBM456207 (R)-6-(3-(difluoromethyl)- 4-(((2-hydroxy-2-(4- methyl-1-oxo-1,3- dihydroisobenzofuran-5- yl)ethyl)amino)methyl)- 1H-pyrazol-1-yl)-4- methylnicotinonitrile::US10723723, Example 93
SMILES Cc1cc(ncc1C#N)-n1cc(CNC[C@H](O)c2ccc3C(=O)OCc3c2C)c(n1)C(F)F
InChI Key InChIKey=AKLSFEFCBKOPIX-IBGZPJMESA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 456207
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 15nMAssay Description:Solutions and reagents: Thallium flux assay was performed using FluxOR kit (F10017, Life Technologies). Loading buffer, assay buffer and stimulus buf...More data for this Ligand-Target Pair