BDBM456222 (R)-4-ethoxy-6-(4-(((2- hydroxy-2-(4-methyl-1- oxo-1,3- dihydroisobenzofuran-5- yl)ethyl)amino)methyl)- 1H-1,2,3-triazol-1- yl)nicotinonitrile::US10723723, Example 156
SMILES CCOc1cc(ncc1C#N)-n1cc(CNC[C@H](O)c2ccc3C(=O)OCc3c2C)nn1
InChI Key InChIKey=OAKHCLBGCUFSPT-IBGZPJMESA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 456222
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 9.70nMAssay Description:Solutions and reagents: Thallium flux assay was performed using FluxOR kit (F10017, Life Technologies). Loading buffer, assay buffer and stimulus buf...More data for this Ligand-Target Pair