BDBM456962 US10738007, Compound ID 27::US11555039, Compound ID 27

SMILES CN1CCc2ccc(NC(=O)c3cccc(c3)[C@@H](CO)NC(=O)c3ccc(cc3)-c3ccncc3)cc2C1=O

InChI Key InChIKey=CENUSJMWBYHADF-MUUNZHRXSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 456962   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Drug Development

US Patent
LigandPNGBDBM456962(US10738007, Compound ID 27 | US11555039, Compound ...)
Affinity DataIC50:  0.390nMAssay Description:n general, kinases regulate many important cellular activities including cell growth, signaling, metabolism, etc. Different kinases have distinct fun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Drug Development

US Patent
LigandPNGBDBM456962(US10738007, Compound ID 27 | US11555039, Compound ...)
Affinity DataIC50:  0.390nMAssay Description:The following assay protocol is for measuring the phosphorylation of a peptide substrate (FAM-KKLRRTLSVA-OH wherein FAM is carboxyfluorescein). The p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent