BDBM456965 US10738007, Compound ID 31::US11555039, Compound ID 31

SMILES CN(C)c1cccc(CNC(=O)c2cccc(c2)[C@@H](CO)NC(=O)c2ccc(cc2)-c2ccncc2)c1

InChI Key InChIKey=YSCICSHOCDXCAS-MUUNZHRXSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 456965   

TargetRho-associated protein kinase 1(Homo sapiens (Human))
Translation Drug Development

US Patent
LigandPNGBDBM456965(US10738007, Compound ID 31 | US11555039, Compound ...)
Affinity DataIC50:  2.10nMAssay Description:The following assay protocol is for measuring the phosphorylation of a peptide substrate (FAM-KKLRRTLSVA-OH wherein FAM is carboxyfluorescein). The p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Drug Development

US Patent
LigandPNGBDBM456965(US10738007, Compound ID 31 | US11555039, Compound ...)
Affinity DataIC50:  1nMAssay Description:n general, kinases regulate many important cellular activities including cell growth, signaling, metabolism, etc. Different kinases have distinct fun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Translation Drug Development

US Patent
LigandPNGBDBM456965(US10738007, Compound ID 31 | US11555039, Compound ...)
Affinity DataIC50:  2.10nMAssay Description:n general, kinases regulate many important cellular activities including cell growth, signaling, metabolism, etc. Different kinases have distinct fun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Drug Development

US Patent
LigandPNGBDBM456965(US10738007, Compound ID 31 | US11555039, Compound ...)
Affinity DataIC50:  1nMAssay Description:The following assay protocol is for measuring the phosphorylation of a peptide substrate (FAM-KKLRRTLSVA-OH wherein FAM is carboxyfluorescein). The p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent