BDBM457012 US10738007, Compound ID 78::US10738007, Compound ID 91::US11555039, Compound ID 91

SMILES COC(=O)N1CCC(CNC(=O)c2cccc(c2)[C@@H](CO)NC(=O)c2ccc(cc2)-c2ccncc2)CC1

InChI Key InChIKey=XESDIZSUBGMYNC-AREMUKBSSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 457012   

TargetRho-associated protein kinase 1(Homo sapiens (Human))
Translation Drug Development

US Patent
LigandPNGBDBM457012(US10738007, Compound ID 78 | US10738007, Compound ...)
Affinity DataIC50:  1.70nMAssay Description:The following assay protocol is for measuring the phosphorylation of a peptide substrate (FAM-KKLRRTLSVA-OH wherein FAM is carboxyfluorescein). The p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translation Drug Development

US Patent
LigandPNGBDBM457012(US10738007, Compound ID 78 | US10738007, Compound ...)
Affinity DataIC50:  0.570nMAssay Description:The following assay protocol is for measuring the phosphorylation of a peptide substrate (FAM-KKLRRTLSVA-OH wherein FAM is carboxyfluorescein). The p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translation Drug Development

US Patent
LigandPNGBDBM457012(US10738007, Compound ID 78 | US10738007, Compound ...)
Affinity DataIC50:  0.570nMAssay Description:n general, kinases regulate many important cellular activities including cell growth, signaling, metabolism, etc. Different kinases have distinct fun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Translation Drug Development

US Patent
LigandPNGBDBM457012(US10738007, Compound ID 78 | US10738007, Compound ...)
Affinity DataIC50:  1.70nMAssay Description:n general, kinases regulate many important cellular activities including cell growth, signaling, metabolism, etc. Different kinases have distinct fun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translation Drug Development

US Patent
LigandPNGBDBM457012(US10738007, Compound ID 78 | US10738007, Compound ...)
Affinity DataIC50:  0.570nMAssay Description:n general, kinases regulate many important cellular activities including cell growth, signaling, metabolism, etc. Different kinases have distinct fun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translation Drug Development

US Patent
LigandPNGBDBM457012(US10738007, Compound ID 78 | US10738007, Compound ...)
Affinity DataIC50:  0.570nMAssay Description:The following assay protocol is for measuring the phosphorylation of a peptide substrate (FAM-KKLRRTLSVA-OH wherein FAM is carboxyfluorescein). The p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent