BDBM457016 US10738007, Compound ID 82::US11555039, Compound ID 82

SMILES CN(C)Cc1cccc(CNC(=O)c2cccc(c2)[C@@H](CO)NC(=O)c2ccc(cc2)-c2cn[nH]c2)c1

InChI Key

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 457016   

TargetRho-associated protein kinase 1(Homo sapiens (Human))
Translation Drug Development

US Patent
LigandPNGBDBM457016(US10738007, Compound ID 82 | US11555039, Compound ...)
Affinity DataIC50:  2nMAssay Description:The following assay protocol is for measuring the phosphorylation of a peptide substrate (FAM-KKLRRTLSVA-OH wherein FAM is carboxyfluorescein). The p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Drug Development

US Patent
LigandPNGBDBM457016(US10738007, Compound ID 82 | US11555039, Compound ...)
Affinity DataIC50:  0.650nMAssay Description:n general, kinases regulate many important cellular activities including cell growth, signaling, metabolism, etc. Different kinases have distinct fun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Translation Drug Development

US Patent
LigandPNGBDBM457016(US10738007, Compound ID 82 | US11555039, Compound ...)
Affinity DataIC50:  2nMAssay Description:n general, kinases regulate many important cellular activities including cell growth, signaling, metabolism, etc. Different kinases have distinct fun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Drug Development

US Patent
LigandPNGBDBM457016(US10738007, Compound ID 82 | US11555039, Compound ...)
Affinity DataIC50:  0.650nMAssay Description:The following assay protocol is for measuring the phosphorylation of a peptide substrate (FAM-KKLRRTLSVA-OH wherein FAM is carboxyfluorescein). The p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent