BDBM457080 (S)-6-((1-amino-1-oxopropan- 2-yl)amino)-2-(5-(4- (trifluoromethyl)phenyl)-3,4- dihydroisoquinolin-2(1H)- yl)pyrimidine-4-carboxamide::US10738026, Compound 22::US11401258, Compound 22
SMILES C[C@H](Nc1cc(nc(n1)N1CCc2c(C1)cccc2-c1ccc(cc1)C(F)(F)F)C(N)=O)C(N)=O
InChI Key InChIKey=RTJIPUIEDQRKRX-ZDUSSCGKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 457080
Affinity DataKi: 317nMAssay Description:On the day of experimentation, cells are prepared by removing media and digesting with appropriate enzymes to suspend cells in external solution.Whol...More data for this Ligand-Target Pair
Affinity DataKi: 317nMAssay Description:Manual Electrophysiology: On the day of experimentation, the 35 mm dish is placed on the stage of an inverted microscope equipped with a perfusion sy...More data for this Ligand-Target Pair
Affinity DataIC50: 428nMAssay Description:Assay Buffer: The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL...More data for this Ligand-Target Pair
Affinity DataIC50: 428nMAssay Description:The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...More data for this Ligand-Target Pair