BDBM457083 6-(5-(4-(trifluoromethyl)- phenyl)-3,4-dihydro- isoquinolin-2(1H)-yl)- picolinamide::US10738026, Compound 25::US11401258, Compound 25

SMILES NC(=O)c1cccc(n1)N1CCc2c(C1)cccc2-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=PDKJRCDTWHBSKE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 457083   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM457083(6-(5-(4-(trifluoromethyl)- phenyl)-3,4-dihydro- is...)
Affinity DataIC50:  987nMAssay Description:Assay Buffer: The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM457083(6-(5-(4-(trifluoromethyl)- phenyl)-3,4-dihydro- is...)
Affinity DataIC50:  987nMAssay Description:The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent