BDBM457087 (S)-6-((1-amino-1-oxopropan- 2-yl)amino)-2-(5-(cyclohex-1- en-1-yl)-3,4-dihydro- isoquinolin-2(1H)- yl)pyrimidine-4-carboxamide::US10738026, Compound 28::US11401258, Compound 28

SMILES C[C@H](Nc1cc(nc(n1)N1CCc2c(C1)cccc2C1=CCCCC1)C(N)=O)C(N)=O

InChI Key InChIKey=KQQNLKRRPXIPSA-AWEZNQCLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 457087   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM457087((S)-6-((1-amino-1-oxopropan- 2-yl)amino)-2-(5-(cyc...)
Affinity DataIC50:  2.84E+3nMAssay Description:Assay Buffer: The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM457087((S)-6-((1-amino-1-oxopropan- 2-yl)amino)-2-(5-(cyc...)
Affinity DataIC50:  2.84E+3nMAssay Description:The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent