BDBM457092 (S)-6-((1-amino-1-oxopropan- 2-yl)amino)-2-(5-cyclohexyl- 3,4-dihydroisoquinolin-2(1H)- yl)pyrimidine-4-carboxamide::US10738026, Compound 31::US11401258, Compound 31

SMILES C[C@H](Nc1cc(nc(n1)N1CCc2c(C1)cccc2C1CCCCC1)C(N)=O)C(N)=O

InChI Key InChIKey=HHIDIFCNHJJOIJ-AWEZNQCLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 457092   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM457092((S)-6-((1-amino-1-oxopropan- 2-yl)amino)-2-(5-cycl...)
Affinity DataIC50:  2.20E+3nMAssay Description:Assay Buffer: The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM457092((S)-6-((1-amino-1-oxopropan- 2-yl)amino)-2-(5-cycl...)
Affinity DataIC50:  2.20E+3nMAssay Description:The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent